Tetrahedron Letters p. 6239 - 6242 (1996)
Update date:2022-08-04
Topics:
Zhao, Zhengyun
Caruthers, Marvin H.
Thymidine deoxyoligonucleotides having a 5'-deoxy-5'-methylidyne phosphonate internucleotide linkage were synthesized. Relative to natural DNA, these oligomers were nuclease resistant and formed duplexes with reduced stability.
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