Diastereoselective synthesis of spongian diterpenes. Total synthesis of the furanoditerpene (-)-spongia-13(16),14-diene

Article abstract of DOI:10.1016/S0040-4020(99)00725-5

An effective diastereoselective synthesis of the marine-sponge metabolite (-)-spongia-13(16),14-diene 1 is achieved starting from S-(+)- carvone via a homochiral phenanthrenone as the key intermediate for the construction of the furan ring system. S-(+)-C