Synthesis of curacin A, an antimitotic cyclopropane-thiazoline from the marine cyanobacterium Lyngbya majuscula

DOI: 10.1016/0040-4039(96)01616-4

Source and publish data:

Tetrahedron Letters p. 7167 - 7170 (1996)

Update date:2022-07-29

Topics:

Authors:

Lai, Jing-Yu

Yu, Jurong

Mekonnen, Belew

Falck Falck

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(96)01616-4

Charette asymmetric cyclopropanation, chiral thiazoline synthesis by thioamide cyclization under modified Mitsunobu conditions, Ti(iPrO)₄/bi-naphthol catalyzed allylstannane addition, and an exceptionally mild two-carbon homologation via dehydrative alkylation with phenylsulfonylacetonitrile/Ph₃P/ADDP convened in an efficient, stereocontrolled route to the title bioactive heterocycle.

Full text of DOI:10.1016/0040-4039(96)01616-4

Products guided by the article

Product name:(2E,4E)-8-(tert-Butyl-diphenyl-silanyloxy)-2-methyl-octa-2,4-dienoic acid ethyl ester

Cas No:182953-77-1

R&D Labs maybe for 182953-77-1

Shanghai doly chemical Co.,Ltd

Contact:+86-21-34716221

Address:No.328,WuHe Roard,MinHang,ShangHai China
Guilin Zhenda Bio-Tech Co., Ltd.

Contact:86-773-3568977

Address:-Yangtang shangshui industry park, Lingui county,
Shanghai He Yang International Trading Co., Ltd.

Contact:+86-21-52043598

Address:Room 816, Blag.5, No.58 Huachi Road
FOSHAN NANHAI ZHONGNAN PHARMACEUTICAL FACTORY

Contact:0086-0757-85609331

Address:XIAHENGTIAN INDUSTRIAL ZONE,SHAYONG VILLAGE,LISHUI TOWN
Chengdu Herbpurify Co., Ltd

website:http://www.herbpurify.com

Contact:0086-028-85249238

Address:Room709-C1,Incubator Building, Tianfu Life Science Park No.88,Keyuan Road,Gaoxin district,Chengdu City,Sichuan Prov,China

Relevant to this article

Synthesis and characterization of intra- and intermolecular hydrogen bonding isomers of P-H (apical) phosphoranes bearing a hydroxyl group and their thermal cyclization

Doi:10.1016/0040-4039(96)01923-5
(1996)
1,3-Diphenylpropan-1,3-diamines IX. Reaction of α-Chlorooxime Ethers with α-Lithiobenzylamines

Doi:10.1007/BF00817268
(1996)
Reductive alkylation of pyridinium salts. Part 2. Utilisation of di-, tetra- and hexa-hydropyridine esters

Doi:10.1039/p19960002553
(1996)
Ruthenium complex catalyzed hydrosilylation of esters: A facile transformation of esters to alkyl silyl acetals and aldehydes

Doi:10.1016/S0040-4039(01)00094-6
(2001)
Triethoxysilane, tetraethoxysilane and hexaethoxydisiloxane - Three complementary reagents for the synthesis of hydrogen-rich silylarenes

Doi:10.1515/znb-2004-0206
(2004)
Ir(I) complexes with oxazoline-thioether ligands: Nucleophilic attack of pyridine on coordinated 1,5-cyclooctadiene and application as catalysts in imine hydrogenation

Doi:10.1016/j.jorganchem.2004.03.015
(2004)

Article Doi