Synthesis and properties of α- and β-oligodeoxynucleotides containing α- and β-1-(2-O-methyl-D-arabinofuranosyl)thymine

Article abstract of DOI:10.1016/0968-0896(96)00117-4

Synthesis of the α- and β-anomer of 2'-OMe-araT (α- and β-1-(2-O-methyl-D-arabinofuranosyl)thymine) and their incorporation into oligodeoxynucleotide (ODN) analogues is described. Condensation of the key arabinofuranose derivative with silylated thymine a