Tetrahedron Letters p. 980 - 982 (2013)
Update date:2022-08-03
Topics:
Dias, Luiz C.
Kuroishi, Paula K.
Polo, Ellen C.
De Lucca Jr., Emílio C.
The first total synthesis of (-)-ericanone was achieved in 10 steps with a 16% overall yield from p-hydroxybenzaldehyde. Notable features of this stereocontrolled approach include a Keck allylation to install the stereocenter at C3 and a 1,5-anti aldol reaction to install the hydroxyl group at C7.
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