Synthesis and biological evaluation of (23R)- and (23S)-24,24-difluoro 1α,23,25-trihydroxyvitamin D3

DOI: 10.1248/cpb.46.1932

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1932 - 1935 (1998)

Update date:2022-08-04

Topics:

Authors:

Iwasaki, Hiroshi

Miyamoto, Yoichi

Hosotani, Ryuzo

Nakano, Yoshio

Konno, Katsuhiro

Takayama, Hiroaki

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.46.1932

The syntheses and biological evaluations of (23R)- and (23S)-24,24- difluoro-1α23,25-trithydroxyvitamin D₃ (3a and 3b), new C-24 fluorinated analogs of 1α-25-dihydroxyvitamin D₃, are described. The syntheses of these compounds were a

Full text of DOI:10.1248/cpb.46.1932

NII-Electronic Library Service

Products guided by the article

Product name:(5Z,7E,20R,23S)-24,24-difluoro-1α,3β-bis<(tert-butyldimethylsilyl)oxy>-23-hydroxy-24-ethoxycarbonyl-9,10-seco-5,7,10(19)-cholatriene

Cas No:183274-06-8

R&D Labs maybe for 183274-06-8

Kono Chem Co.,Ltd

website:http://www.konochem.com

Contact:86-29-86107037-8015

Address:No.11 Daqing Road,Lianhu District,Xi’an 710082,China
Naturalin Bio-Resource Co., Ltd

website:http://www.naturalin.com

Contact:+86-0731-84430651

Address:B1-402, Lu-Valley Enterprise Square.No.27 Wenxuan Road. Lu-Valley Hi-Tech District.
Sino Rarechem Labs Co.Ltd

Contact:+86-0512-62857507

Address:Boji Science Park, No1688C,Taishan road, Suzhou ,China
Chinese Peptide Company

Contact:86-571-86737118-8689

Address:No.69, 12 Street, HEDA, Hangzhou, Zhejiang, China
Maithili Life Sciences

Contact:+91 9963263336

Address:Plot#146A, IDA Mallapur, Hyderabad - 500072

Relevant to this article

PROTONATION AND METHYLATION REACTIONS OF 2-PYRIDYL-PALLADIUM(II) AND -PLATINUM(II) COMPLEXES

Doi:10.1016/S0022-328X(00)98785-0
(1983)
Synthesis of ethyl 2-(4-chlorophenyl)-5-(2-furyl)-4-oxazoleacetate, a hypolipidemic agent, and related compounds

Doi:10.1021/jm00401a021
(1988)
Ruthenium-catalyzed C6-propenylation reactions of substituted pyridine derivatives: Directed and direct C-H activation

Doi:10.1002/chem.201202379
(2012)
Facile Route to 2-Fluoropyridines via 2-Pyridyltrialkylammonium Salts Prepared from Pyridine N-Oxides and Application to ¹⁸F-Labeling

Doi:10.1021/acs.orglett.5b01703
(2015)
A metathesis approach for the preparation of polyhydroxylated compounds as head groups in surfactant synthesis

Doi:10.1002/ejoc.200500614
(2006)
A DIASTEREOSELECTIVE SYNTHESIS OF 4(RS), 6(SR)-MERCAPTOMETHYLMEVALONOLACTONE, A KEY INTERMEDIATE IN THE PREPARATION OF A NEW CLASS OF INHIBITORS OF HMG-CoA REDUCTASE

Doi:10.1016/S0040-4039(00)94530-1
(1983)

Article Doi