Synthesis and biological evaluation of (23R)- and (23S)-24,24-difluoro 1α,23,25-trihydroxyvitamin D3

DOI: 10.1248/cpb.46.1932

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1932 - 1935 (1998)

Update date:2022-08-04

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Authors:

Iwasaki, Hiroshi

Miyamoto, Yoichi

Hosotani, Ryuzo

Nakano, Yoshio

Konno, Katsuhiro

Takayama, Hiroaki

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Article abstract of DOI:10.1248/cpb.46.1932

The syntheses and biological evaluations of (23R)- and (23S)-24,24- difluoro-1α23,25-trithydroxyvitamin D₃ (3a and 3b), new C-24 fluorinated analogs of 1α-25-dihydroxyvitamin D₃, are described. The syntheses of these compounds were a

Full text of DOI:10.1248/cpb.46.1932

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