Synthesis and biological evaluation of (23R)- and (23S)-24,24-difluoro 1α,23,25-trihydroxyvitamin D3

DOI: 10.1248/cpb.46.1932

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1932 - 1935 (1998)

Update date:2022-08-04

Topics:

Authors:

Iwasaki, Hiroshi

Miyamoto, Yoichi

Hosotani, Ryuzo

Nakano, Yoshio

Konno, Katsuhiro

Takayama, Hiroaki

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.46.1932

The syntheses and biological evaluations of (23R)- and (23S)-24,24- difluoro-1α23,25-trithydroxyvitamin D₃ (3a and 3b), new C-24 fluorinated analogs of 1α-25-dihydroxyvitamin D₃, are described. The syntheses of these compounds were a

Full text of DOI:10.1248/cpb.46.1932

NII-Electronic Library Service

Products guided by the article

Product name:(5Z,7E,20R,23S)-24,24-difluoro-1α,3β-bis<(tert-butyldimethylsilyl)oxy>-23-hydroxy-24-ethoxycarbonyl-9,10-seco-5,7,10(19)-cholatriene

Cas No:183274-06-8

R&D Labs maybe for 183274-06-8

Chuzhou Baiao Biologhy S&T Co., Ltd.

Contact:+86-25-83212599；+86-25-83212699 13705185959

Address:Room 905, Tianzheng International Platza, No.399, Zhongyang Road ,Nanjing, Jiangsu Province, China
Xiamen Huasing Chemicals Co.Ltd.

Contact:0086-592-6228397

Address:NO.24, Xinglin North 2nd Road,Jimei district
Nanjing Vincero International Trading Co.,Ltd

Contact:8618936897229

Address:NO.68, ZhuShan Road, JiangNing WanDa Plaza, Building E Room 1703
Henan Techway Chemical Co.,Ltd.

website:http://www.techwaychem.com

Contact:+86-371-66380080

Address:No.27 Shunhe Road,
Ningbo J&S Botanics Inc.

Contact:86-574-26865651

Address:529 YuanBaoShan Road, Beilun District

Relevant to this article

PROTONATION AND METHYLATION REACTIONS OF 2-PYRIDYL-PALLADIUM(II) AND -PLATINUM(II) COMPLEXES

Doi:10.1016/S0022-328X(00)98785-0
(1983)
Synthesis of ethyl 2-(4-chlorophenyl)-5-(2-furyl)-4-oxazoleacetate, a hypolipidemic agent, and related compounds

Doi:10.1021/jm00401a021
(1988)
Ruthenium-catalyzed C6-propenylation reactions of substituted pyridine derivatives: Directed and direct C-H activation

Doi:10.1002/chem.201202379
(2012)
Facile Route to 2-Fluoropyridines via 2-Pyridyltrialkylammonium Salts Prepared from Pyridine N-Oxides and Application to ¹⁸F-Labeling

Doi:10.1021/acs.orglett.5b01703
(2015)
A metathesis approach for the preparation of polyhydroxylated compounds as head groups in surfactant synthesis

Doi:10.1002/ejoc.200500614
(2006)
A DIASTEREOSELECTIVE SYNTHESIS OF 4(RS), 6(SR)-MERCAPTOMETHYLMEVALONOLACTONE, A KEY INTERMEDIATE IN THE PREPARATION OF A NEW CLASS OF INHIBITORS OF HMG-CoA REDUCTASE

Doi:10.1016/S0040-4039(00)94530-1
(1983)

Article Doi