Tandem carbophilic addition-N-acyliminium ion cyclization for the synthesis of functionalized pyrrolo[2,1-a]isoquinolones: Key intermediate for the preparation of Erythrina-type alkaloids

Article abstract of DOI:10.1016/0040-4039(96)01745-5

Sequential carbophilic addition of organolithium reagents-N-acyliminium ion cyclization of N-phenenethylsuccinimide 3 yields pyrrolo[2,1-a]isoquinolones 1 in high yields, with the possibility of varying the substituent at C-10b by changing the organolithi