A novel synthetic approach to the preparation of various α,α-difluoroesters

DOI: 10.1016/S0040-4039(96)02043-6

Source and publish data:

Tetrahedron Letters p. 8759 - 8762 (1996)

Update date:2022-08-04

Topics:

Authors:

Bildstein, Sylvia

Ducep, Jean-Bernard

Jacobi, Detlef

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Article abstract of DOI:10.1016/S0040-4039(96)02043-6

Treatment of readily available α-fluoro-β-hydroxy-α-phenylthioesters 4 with DAST afforded α,α-difluoro-β-phenylthioesters 6 which are of interest to synthesize gem-difluorinated derivatives.

Full text of DOI:10.1016/S0040-4039(96)02043-6

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