Synthesis of 3,3-Bis(3-fluorophenyl)-[2,3-3h2]-1-propanamine Hydrochloride ([3H2]-NPS 846 · HCl): A novel ligand for the NMDA receptor

DOI: 10.1002/(SICI)1099-1344(199806)41:6<535::AID-JLCR101>3.0.CO;2-P

Source and publish data:

Journal of labelled compounds and radiopharmaceuticals p. 535 - 543 (1998)

Update date:2022-08-04

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Authors:

Moe, Scott T.

Smith, Daryl L.

By, Kolbot

Egan, Judith A.

Filer, Crist N.

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Article abstract of DOI:10.1002/(SICI)1099-1344(199806)41:6<535::AID-JLCR101>3.0.CO;2-P

3,3-Bis(3-fluorophenyl)-1-propanamine hydrochloride (NPS 846-HCl, 1a) is representative of a new class of diphenylpropylamine NMDA receptor antagonists. The corresponding radiolabelled ligand was prepared by catalytic tritiation of its precursor olefin (4

Full text of DOI:10.1002/(SICI)1099-1344(199806)41:6<535::AID-JLCR101>3.0.CO;2-P

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