Synthesis of 4,5,6-trisubstituted 3-cyanopyridine-2(1H)-thiones based on α-substituted β-diketones

Article abstract of DOI:10.1007/BF01431119

5-Substituted 3-cyano-4,6-dimethylpyridine-2(1H)-thiones were synthesized by the reaction of α-substituted β-diketones with cyanothioacetamide in the presence of triethylamine. The compounds synthesized were converted into thieno[2,3-b]pyridines by treatment with organic halides and KOH.