Tetrahedron Letters p. 1297 - 1300 (1997)
Update date:2022-07-31
Topics:
Patt, William C.
Massa, Mark A.
The first total synthesis of WS75624 B, 1, an endothelin converting enzyme inhibitor produced in a fermentation broth of Saccharothrix sp. No. 75624 is reported herein. WS75624 B is synthesized in 14 steps from commercially available kojic acid, 2. The synthetic methodology allows for facile substitution at multiple sites on the molecule.
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Doi:10.1021/jo961824v
(1997)Doi:10.1021/ic9613117
(1997)Doi:10.1002/jhet.5570340128
(1997)Doi:10.1021/jo961820q
(1997)Doi:10.1021/jm970106d
(1997)Doi:10.1021/ja01571a075
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