A nonpeptidic agonist ligand of the human C5a receptor: Synthesis, binding affinity optimization and functional characterization

DOI: 10.1016/S0960-894X(96)00606-3

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 213 - 218 (1997)

Update date:2022-08-03

Topics: Synthesis Ligand Optimization binding affinity Functional Characterization Experimental

Authors:

De Laszlo

Allen Allen

Ondeyka Ondeyka

Rivero Rivero

Malkowitz

Molineaux

Siciliano

Springer

Greenlee

Mantlo Mantlo

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Article abstract of DOI:10.1016/S0960-894X(96)00606-3

The structural optimization for binding affinity and attempted modification of agonist function of a nonpeptide ligand of the human C5a receptor is described.

Full text of DOI:10.1016/S0960-894X(96)00606-3

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