Synthesis of (+)-Ambrein

DOI: 10.1016/S0040-4020(97)00103-8

Source and publish data:

Tetrahedron p. 3527 - 3536 (1997)

Update date:2022-08-04

Topics: Synthesis Yield Catalyst Purification Reaction Conditions

Authors:

Tanimoto, Hisahide

Oritani, Takayuki

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Article abstract of DOI:10.1016/S0040-4020(97)00103-8

Enantiomerically pure (+)-Ambrein was synthesized from (+)-drimane-8,11-diol prepared via lipase catalyzed kinetic resolution, and easily prepared (i)-γ-cyclogeraniol.

Full text of DOI:10.1016/S0040-4020(97)00103-8

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Product name:(S)-2-Chloromethyl-1,1-dimethyl-3-methylene-cyclohexane

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