Synthesis of N-acetylglucosaminyl- and N-acetylgalactosaminylceramides as cerebroside analogs and their anti-human immunodeficiency virus type 1 activities

DOI: 10.1248/cpb.45.402

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 402 - 405 (1997)

Update date:2022-08-05

Topics:

Authors:

Ikeda, Kiyoshi

Asahara, Tsuyoshi

Achiwa, Kazuo

Hoshino, Hiroo

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.45.402

Monoglycosylceramide derivatives containing mimicks of ceramide were synthesized as cerebroside analogs from D-glucosamine or D-galactosamine derivatives and N-benzyloxycarbonyl-L-serine myristylamide by using trimethylsilyl trifluoromethanesulfonate (TMSOTf) as a promoter. The synthesized sulfated glycolipids show moderate anti-HIV-1 activities.

Full text of DOI:10.1248/cpb.45.402

NII-Electronic Library Service

Products guided by the article

Product name:N-benzyloxycarbonyl-O-(3,4,6-tri-O-acetyl 2-chloroacetylamino-2-deoxy-β-D-glucopyranosyl)-L-serine myristylamide

Cas No:188630-17-3

R&D Labs maybe for 188630-17-3

WEIFANG RICHEM INTERNATIONAL LTD

Contact:86-536-2222176

Address:weifang,shandong
Huayi Isotopes Co.

Contact:+ 86 512 52491118

Address:1 Fuyu Road, Haiyu TownChangshu, Jiangsu, China
Wuhan Fortuna Chemical Co.,Ltd

website:http://www.fortunachem.com

Contact:86-27-59207850

Address:Add: Room 2015, No.2 Building, Kaixin Mansion No.107 Jinqiao Avenue, Wuhan, China
Zhejiang Sucon Silicone Co.,Ltd

Contact:+86-575-88046692

Address:Qisheng Rd., Paojiang Industrial Zone, Shaoxing, Zhejiang, China.
Huzhou City Linghu Xinwang Chemical Co.,Ltd.

Contact:86-572-3948695/3945236

Address:huzhou

Relevant to this article

Competitive acetylide C-C bond scission vs formation of a quadruply bridging carbonyl ligand. X-ray crystal structures of the two pentanuclear clusters Cp*₃W₃Ru₂(μ₄-C)(μ ₃-CPh)(CO)₉ and Cp*₃W₃Ru₂(μ₃-CCBu ^t)(CO)₉

Doi:10.1021/om9610410
(1997)
Modeling, chemistry, and biology of the benzolactam analogues of indolactam V (ILV). 2. Identification of the binding site of the benzolactams in the CRD2 activator-binding domain of PKCδ and discovery of an ILV analogue of improved isozyme selectivity

Doi:10.1021/jm960875h
(1997)
The Reactions of 4,5-Dehydrotropone with 4-Phenyloxazols

Doi:10.1016/S0040-4039(00)74423-6
(1994)
On the chemistry of gallium. 10. N-trimethylsilyl substituted aminogallanes

Doi:10.1002/zaac.19976230183
(1997)
Synthetic Study of Kedarcidin Chromophore: Advanced Models and Their Chemical Behavior

Doi:10.1055/s-1997-780
(1997)
Development of a Hypusine Reagent for Peptide Synthesis

Doi:10.1021/jo970119z
(1997)

Article Doi