Quantitative structure-activity relationships of benzoyliminothiadiazoline derivatives as angiotensin as II receptor antagonists

DOI: 10.1016/S0960-894X(97)00026-7

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 385 - 388 (1997)

Update date:2022-08-04

Topics:

Authors:

Hirata, Terukage

Goto, Satoru

Tamura, Koichi

Okuhira, Masayasu

Nagao, Yoshimitsu

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(97)00026-7

Syntheses and biological activities of benzoyliminothiadiazoline derivatives which have potential affinities for angiotensin II receptor are described. The contributions of substituent CRI) on the benzene ring in benzoyl moiety and 5-position substituent (R²) on the 1,3,4-thiadiazoline ring were quantitatively investigated.

Full text of DOI:10.1016/S0960-894X(97)00026-7

Products guided by the article

Product name:5-methyl-3-[2'-(1-trityl-1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-[1,3,4]thiadiazol-2-ylideneamine

Cas No:188738-98-9

R&D Labs maybe for 188738-98-9

Linyi Shengxin Pharmaceutical R&D Co., Ltd

Contact:+86-18653953873

Address:West First of Yufeng Road, Yishui County
ShanDong XinDa Chemical CO.,LTD(expird)

Contact:086-0311-87580543

Address:No.168, High Technology Development Zone Jinan Shandong China
Linyi Shengxin Pharmaceutical R&D Co., Ltd

Contact:+86-18653953873

Address:West First of Yufeng Road, Yishui County
ShangHai BMG Chemical Co., Ltd

Contact:+86-13524845543

Address:Room 602, no 291 sikai road shanghai
SuZhou LaiTeou

Contact:+86-0512-88957371

Address:shanghai

Relevant to this article

Enolate Additions to a Chiral 3-Hydroxypropionate 2,3-Dication Equivalent. Enantioselective Synthesis of β,δ-Dihydroxy Esters

Doi:10.1021/jo9621940
(1997)
Trifluoromethyl-substituted pyridines through displacement of iodine by in situ generated (trifluoromethyl)copper

Doi:10.1002/1099-0690(20021)2002:2<327::AID-EJOC327>3.0.CO;2-V
(2002)
Doi:10.1021/ja00828a055
(1974)
Doi:10.1021/ja01072a033
(1964)
Synthesis of peptidyl aldehydes from thiazolidines

Doi:10.1016/S0040-4039(97)00383-3
(1997)
Anticancer and antiviral effects and inactivation of S-adenosyl-L- homocysteine hydrolase with 5'-carboxaldehydes and oximes synthesized from adenosine and sugar-modified analogues

Doi:10.1021/jm960828p
(1997)

Article Doi