Synthesis of peptidyl aldehydes from thiazolidines

DOI: 10.1016/S0040-4039(97)00383-3

Source and publish data:

Tetrahedron Letters p. 2459 - 2462 (1997)

Update date:2022-08-04

Topics:

Authors:

Galeotti, Nathalie

Plagnes, Eric

Jouin, Patrick

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Article abstract of DOI:10.1016/S0040-4039(97)00383-3

Peptidyl aldehydes were synthesized using thiazolidine peptides as precursors. Hydrolysis of the heterocycles is easily accomplished using cupper salts to furnish the peptidyl aldehydes with very good yield and with no epimerization.

Full text of DOI:10.1016/S0040-4039(97)00383-3

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Product name:(R)-2-((S)-1-tert-Butoxycarbonylamino-2-phenyl-ethyl)-3-methyl-thiazolidine-4-carboxylic acid methyl ester

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