A highly stereoselective synthesis of (2S,3S)-β-hydroxyleucine

Article abstract of DOI:10.1016/S0040-4039(97)00207-4

A highly diastereoselective nucleophilic addition of Grignard reagent to N,N-dibenzyl-O-TBS-serinal 3 was the key step in the present synthesis of (2S,3S)-β-hydroxyleucine 1.