Xanthene derived potent nonpeptidic inhibitors of recombinant human calpain I

DOI: 10.1016/S0960-894X(96)00286-7

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1619 - 1622 (1996)

Update date:2022-08-02

Topics:

Authors:

Chatterjee, Sankar

Iqbal, Mohamed

Kauer, James C.

Mallamo, John P.

Senadhi, Shobha

Mallya, Satish

Bozyczko-Coyne, Donna

Siman, Robert

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Article abstract of DOI:10.1016/S0960-894X(96)00286-7

Novel and potent, xanthene derived reversible aldehyde (7c) and α- ketocarboxamide (10a), and irreversible fluoromethyl ketone (10b) inhibitors of recombinant human calpain I are described.

Full text of DOI:10.1016/S0960-894X(96)00286-7

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