The preparation of 2-hydroxyethyl-2,3-dihydro-2H-1,4-benzoxazin-3(4H)- one derivatives

Article abstract of DOI:10.1080/00397919808004455

An efficient synthesis of 2-hydroxyethyl-2,3-dihydro-2H-1,4-benzoxazin- 3(4H)-one derivatives is described using α-bromo-γ-butyrolactone as a bis- electrophile containing a latent hydroxyethyl functional group.

Full text of DOI:10.1080/00397919808004455

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The Preparation of
2-Hydroxyethyl-2,3-
dihydro-2h-1,4-
benzoxazin-3(4h)-one
Derivatives
R. F. Frechette a & M. J. Beach a
a The R. W. Johnson Pharmaceutical Research
Institute , 1000 Route 202, P.O. Box 300,
Raritan, NJ, 08869
Published online: 22 Aug 2006.
To cite this article: R. F. Frechette & M. J. Beach (1998) The Preparation of 2-
Hydroxyethyl-2,3-dihydro-2h-1,4-benzoxazin-3(4h)-one Derivatives, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 28:18, 3471-3478, DOI: 10.1080/00397919808004455
To link to this article: http://dx.doi.org/10.1080/00397919808004455
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