Synthesis of natural and non natural orthogonally protected lanthionines from N-tritylserine and allo-threonine derivatives

DOI: 10.1016/S0957-4166(97)00109-2

Source and publish data:

Tetrahedron Asymmetry p. 1453 - 1465 (1997)

Update date:2022-07-29

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Authors:

Dugave, Christophe

Menez, Andre

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Article abstract of DOI:10.1016/S0957-4166(97)00109-2

The reactivity of electrophiles derived from N-tritylserine, threonine and allothreonine esters toward a selection of nucleophiles was investigated. Best yields from substitution products were obtained with N-trityliodoalanine and soft nucleophiles such a

Full text of DOI:10.1016/S0957-4166(97)00109-2

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Product name:(R)-3-[(R)-2-tert-Butoxycarbonyl-2-(9H-fluoren-9-ylmethoxycarbonylamino)-ethylsulfanyl]-2-(trityl-amino)-propionic acid benzyl ester

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