Bioorganic and Medicinal Chemistry Letters p. 762 - 766 (2008)
Update date:2022-08-03
Topics:
Zhang, Honglu
Xu, Yong
Markadieu, Nicolas
Beauwens, Renaud
Erneux, Christophe
Prestwich, Glenn D.
Metabolically-stabilized analogs of PtdIns(3,4,5)P3 have shown long-lived agonist activity for cellular events mediated by this phosphoinositide. We describe an efficient method for the total asymmetric synthesis of the trisphosphorothioate (PT
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