Tetrahedron p. 8751 - 8778 (1997)
Update date:2022-08-03
Topics: Synthesis Biological Evaluation Design Mimetics
Nicolaou
Trujillo, John I.
Chibale, Kelly
The design, synthesis and preliminary biological evaluation of carbohydrate-based non-peptide mimetics of the potent peptidic antagonist of α(v)β3 and α(v)β5, pentapeptide cRGDFV (1) is presented. The design was based on the NMR-determined structure of 1.
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Doi:10.3987/COM-97-7803
(1997)Doi:10.1016/S0223-5234(97)81679-0
(1997)Doi:10.1021/jo01258a040
(1969)Doi:10.1021/ja1083915
(2011)Doi:10.1021/ja01005a023
(1968)Doi:10.1021/ja01007a029
(1968)
