Tetrahedron p. 8751 - 8778 (1997)
Update date:2022-08-03
Topics: Synthesis Biological Evaluation Design Mimetics
Nicolaou
Trujillo, John I.
Chibale, Kelly
The design, synthesis and preliminary biological evaluation of carbohydrate-based non-peptide mimetics of the potent peptidic antagonist of α(v)β3 and α(v)β5, pentapeptide cRGDFV (1) is presented. The design was based on the NMR-determined structure of 1.
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