
Tetrahedron Letters p. 5485 - 5488 (1997)
Update date:2022-08-02
Topics:
Grabowski, Stefan
Armbruster, Joachim
Prinzbach, Horst
meso-Diamino-di(tri,tetr)ols 1-8 were synthesized starting from cheap carbocyclic olefins and cis-diepoxy derivatives. Enantioselective hydrolysis of the corresponding bis(phenylacet)amides with penicillin amidase from E. coli (EC 3.5.1.11) was effected in good yields (73-90%) and with high optical purities (ee 91 - >97).
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Doi:10.1021/ja01103a541
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(2018)