One-pot synthesis of (3R)-hydroxy-β-lactams via enolates of 2-tert-butyl-1,3-dioxolan-4-ones. Part 1

Article abstract of DOI:10.1016/S0957-4166(97)00303-0

Seebach's synthetic method of self-regeneration of stereocenters 'SRS' has been applied to the addition reaction of diphenylimine 1 to the lithium enolates of (2S,5S)-2-(tert-butyl)-5-methyl-1,3-dioxolan-4-one 2a and of (2S,5S)-2-(tert-butyl)-5-phenyl-1,3