Tetrahedron p. 11731 - 11744 (1997)
Update date:2022-09-26
Topics:
Bailey, Jonathan H.
Cherry, David T.
Crapnell, Katherine M.
Moloney, Mark G.
Shim, Sung Bo
Bamford, Mark J.
Lamont, R. Brian
The α,β-unsaturatcd bicyclic lactams 3a,c, prepared from (S)-pyroglutamic acid, are useful substrates for cycloaddition reactions, giving excellent regio- and diastereocontrol; however, lactam 3c has very superior reactivity with several dienes and dipoles under mild reaction conditions.
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(2013)
