Tetrahedron Letters p. 6677 - 6680 (1997)
Update date:2022-08-05
Topics:
Li, Hao
Sakamoto, Takeshi
Kikugawa, Yasuo
Introduction of alkyl groups with trialkylaluminums in the 5-position of the pyroglutamic ring system without ring opening and subsequent hydrogenation over Pt/C lead to exclusively cis-5-alkyl-(S)-prolines without epimerization of the chiral centre.
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(1997)
