Stereoselective synthesis of cis-5-alkyl-(S)-prolines from (S)-pyroglutamic acid via 5-alkyl-5-hydroxy-(S)-prolines

DOI: 10.1016/S0040-4039(97)01563-3

Source and publish data:

Tetrahedron Letters p. 6677 - 6680 (1997)

Update date:2022-08-05

Topics:

Authors:

Li, Hao Li, Hao

Sakamoto, Takeshi

Kikugawa, Yasuo

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(97)01563-3

Introduction of alkyl groups with trialkylaluminums in the 5-position of the pyroglutamic ring system without ring opening and subsequent hydrogenation over Pt/C lead to exclusively cis-5-alkyl-(S)-prolines without epimerization of the chiral centre.

Full text of DOI:10.1016/S0040-4039(97)01563-3

Products guided by the article

Product name:(S)-5-Hydroxy-5-methyl-pyrrolidine-1,2-dicarboxylic acid 2-benzyl ester 1-methyl ester

Cas No:196411-25-3

R&D Labs maybe for 196411-25-3

Hangzhou Deli Chemical Co.,Ltd.

website:http://www.dlchemical.com

Contact:86 571 28006267

Address:Tangxi Industrial Area, Yuhang District, Hangzhou
Zibo Jujin Chemical Industry Co., Ltd.（Dongming Jujin Chemical Industry Co., Ltd. ）

Contact:+86-533-2975022

Address:No.99 Shanquan Road, Zhangdian District
Hangzhou Dingyan Chem Co., Ltd

website:http://www.dingyanchem.com

Contact:86-571-87157530-8002

Address:RM.1118,NO.1 Building, Baiyun Tower,Jianggan Area, Hangzhou city, China,310004
X.T.Y Environ-Tech Co.,Ltd

Contact:+86-310-7092106

Address:Quzhou Modern & New Industrial Park, Handan, Hebei 057250, China
QINGDAO DEVELOP chemistry Co.,Limited

Contact:+86-532-85807910

Address:98#Nanjing Road, Qingdao, China 266071

Relevant to this article

Inter- and intramolecular experimental and calculated equilibrium isotope effects for (silox)₂((t)Bu₃SiND)TiR + RH (silox = (t)Bu₃SiO): Inferred kinetic isotope effects for RH/D addition to transient (silox)₂Ti

Doi:10.1021/ja000112q
(2000)
A versatile route to conjugated hydroxy (E,Z,E,E)-tetraenoic acids: Highly chemo- and stereoselective synthesis of lipoxin B₄

Doi:10.1016/S0957-4166(97)00333-9
(1997)
Synthesis of [1-Isoleucine-, 3-proline-, and 5-alanine]-angiotensins. II.

Doi:10.1021/bi00850a016
(1968)
Synthesis of conagenin analogs modified at 3'-carbon atom

Doi:10.1016/S0040-4020(97)00877-6
(1997)
The benzyloxycarbonyl protective group: A good alternative to the benzyl protective group in the glycopyranoside and glycofuranoside series

Doi:10.1016/S0040-4039(97)10021-1
(1997)
Application of carbodiimide in heterocyclic synthesis: New facile synthesis of 2-aminoimidazolinone derivatives

Doi:10.1080/00397919708007088
(1997)

Article Doi