
Angewandte Chemie - International Edition in English p. 1745 - 1747 (1997)
Update date:2022-09-26
Topics:
Schopfer
Stahl
Brandl
Hoffmann
Almost congruent with the natural prototype 1, βII-hairpin mimetic 2 was obtained through rational conformation design. The hydrocarbon backbone of 2 provides optimal preorganization of the hydrogen bond, which is decisive for inducing a β-sheet conformation.
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Doi:10.1016/S0040-4039(97)01793-0
(1997)Doi:10.1016/S0040-4020(97)00992-7
(1997)Doi:10.1002/anie.199723581
(1997)Doi:10.1021/ja9708777
(1997)Doi:10.1002/cber.19971301027
(1997)Doi:10.1016/S0040-4039(00)89684-7
(1968)