ENZYMATIC RESOLUTION OF METHYL 2-ALKYL-2-ARYLACETATES

DOI: 10.1016/S0040-4039(01)93421-5

Source and publish data:

Tetrahedron Letters p. 7053 - 7056 (1989)

Update date:2022-08-03

Topics:

Authors:

Ahmar, M.

Girard, C.

Bloch, R.

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Article abstract of DOI:10.1016/S0040-4039(01)93421-5

Horse liver esterase, used as its inexpensive commercial acetone powder, catalyzes the selective hydrolysis of methy 2-alkyl-2-arylacetates to afford R(-)-2-alkyl-2-arylacetic acids and S(+)-methyl 2-alkyl-2-arylacetates.

Full text of DOI:10.1016/S0040-4039(01)93421-5

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Product name:Benzeneacetic acid, 4-chloro-a-(1-Methylethyl)-, Methyl ester, (R)-

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