165. Synthesis of 4′-C-acylated thymidines

DOI: 10.1002/hlca.19960790720

Source and publish data:

Helvetica Chimica Acta p. 1980 - 1994 (1996)

Update date:2022-07-31

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Authors:

Marx, Andreas

Erdmann, Peter

Senn, Martin

Koerner, Steffi

Jungo, Tobias

Petretta, Mario

Imwinkelried, Petra

Dussy, Adrian

Kulicke, Klaus J.

Macko, Ludwig

Zehnder, Margareta

Giese, Bernd

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Article abstract of DOI:10.1002/hlca.19960790720

Two synthetic pathways towards 4′-C-acylthymidines are presented. These modified mononucleosides are precursors of the 2′-deoxyribonucleotide 4′-C-radical. They were converted into their corresponding 3′-O-[(2-cyanoethyl) N,N-diisopropylphosphoramidites]

Full text of DOI:10.1002/hlca.19960790720

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