Stereospecific synthesis of 2'-deoxy pyrimidine and 5,6-dihydro 5-hydroxy thymidine nucleosides

Article abstract of DOI:10.1016/S0040-4039(97)01659-6

An economic and versatile synthesis of 2'-deoxy and 2',3'-dideoxy pyrimidine nucleosides is described. Readily available oxazoline 1 is condensed with glycidate 2 to give anhydro nucleoside 3. This is converted to the title compounds following established routes.