Carbamate derived stable precursors for generating chiral azomethine ylids under mild conditions.

DOI: 10.1016/S0040-4020(97)00788-6

Source and publish data:

Tetrahedron p. 12671 - 12678 (1997)

Update date:2022-08-04

Topics:

Authors:

Alker, David

Harwood, Laurence M.

Williams, C. Eleri

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Article abstract of DOI:10.1016/S0040-4020(97)00788-6

We describe the evolution of stable azomethine ylid precursors which avoid the need for an aldehyde in the ylid generation step. tert-Butyl carbamate derivative (16) demonstrates comparable efficiency to the standard method of ylid generation and trapping, but permits use of milder conditions.

Full text of DOI:10.1016/S0040-4020(97)00788-6

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