Carbamate derived stable precursors for generating chiral azomethine ylids under mild conditions.

DOI: 10.1016/S0040-4020(97)00788-6

Source and publish data:

Tetrahedron p. 12671 - 12678 (1997)

Update date:2022-08-04

Topics:

Authors:

Alker, David

Harwood, Laurence M.

Williams, C. Eleri

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(97)00788-6

We describe the evolution of stable azomethine ylid precursors which avoid the need for an aldehyde in the ylid generation step. tert-Butyl carbamate derivative (16) demonstrates comparable efficiency to the standard method of ylid generation and trapping, but permits use of milder conditions.

Full text of DOI:10.1016/S0040-4020(97)00788-6

Products guided by the article

Product name:Carbamic acid, [(dimethylamino)methyl]-, 1,1-dimethylethyl ester (9CI)

Cas No:197167-82-1

R&D Labs maybe for 197167-82-1

Shandong Zhongcheng Barium Salt Co., Ltd

Contact:+86-15725732638

Address:No.29 baoxi road, hi-tech zone, zibo, shandong
Shanghai united Scientific Co.,Ltd.

Contact:+86-21-53535353

Address:28F No.900 huaihai Road Shanghai China
Zhangjiagang Golden Reach Fine Chemical Co.,LTD.

Contact:+86-512-6585 6968

Address:Changfu Road， Dongsha Chemical Industry Park, Zhangjiagang City, Jiangsu Province, China
Beijing eternalchem Co,. Ltd

Contact:+86-10-59484199

Address:No.58-A1026 Liangguan Street
Suzhou Tianma Specialty Chemicals Co.,Ltd

Contact:+86-512-68090577

Address:#199, Huayuan Rd, Mudu, Suzhou, Jiangsu, CHINA

Relevant to this article

Utilization of industrial waste materials, 11: Synthesis of new, chiral β-sec-amino alcohols - Diastereodivergent addition of grignard reagents to α-amino aldehydes based on the (all-R)-2-azabicyclo[3.3.0]octane system

Doi:10.1002/jlac.199719971016
(1997)
Doi:10.1021/jf60159a017
(1968)
Quinols as novel therapeutic agents. 7. Synthesis of antitumor 4-[1-(arylsulfonyl-1H-indol-2-yl)]-4-hydroxycyclohexa-2,5-dien-1-ones by Sonogashira reactions

Doi:10.1021/jm061163m
(2007)
Meerwein-Ponndorf-Verley-type reductive acetylation of carbonyl compounds to acetates by lanthanide complexes in the presence of isopropenyl acetate

Doi:10.1016/S0040-4039(00)00012-5
(2000)
Discovery of Aromatic Carbamates that Confer Neuroprotective Activity by Enhancing Autophagy and Inducing the Anti-Apoptotic Protein B-Cell Lymphoma 2 (Bcl-2)

Doi:10.1021/acs.jmedchem.7b01199
(2017)
Stereoselective synthesis of (+)-IKD-8344

Doi:10.1016/j.tet.2007.07.005
(2007)

Article Doi