An efficient access to the enantiomers of α-methyl-4-carboxyphenylglycine via a hydantoin route using a practical variant of preferential crystallization. AS3PC (auto seeded programmed polythermic preferential crystallization)

DOI: 10.1016/S0957-4166(97)00349-2

Source and publish data:

Tetrahedron Asymmetry p. 2913 - 2920 (1997)

Update date:2022-08-05

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Authors:

Ndzie Ndzie

Cardinael

Schoofs Schoofs

Coquerel

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Article abstract of DOI:10.1016/S0957-4166(97)00349-2

The enantiomers are obtained in preparative amounts without a resolving agent via the following sequence: hydantoin synthesis, resolution by entrainment, and ring cleavage by means of hydrolysis in basic conditions. The new variant of preferential crystal

Full text of DOI:10.1016/S0957-4166(97)00349-2

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