8-Aminoquinolines as anticoccidials - I

DOI: 10.1016/S0960-894X(97)10024-5

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2585 - 2588 (1997)

Update date:2022-08-03

Topics:

Authors:

Armer, Richard E.

Barlow, Jacqueline S.

Dutton, Christopher J.

Greenway, David H.J.

Greenwood, Sean D.W.

Lad, Nita

Tommasini, Ivan

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Article abstract of DOI:10.1016/S0960-894X(97)10024-5

The proposed ring metabolites of the 8-aminoquinoline antimalarial, pentaquine, 1, have been synthesised and their biological activity as anticoccidial agents investigated in vivo. Several analogues in which this metabolic pathway had been blocked were also synthesised and their anticoccidial activity measured.

Full text of DOI:10.1016/S0960-894X(97)10024-5

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