A novel synthesis of 9,13-dicis double bonds locked retinoids

DOI: 10.1016/S0040-4039(97)10246-5

Source and publish data:

Tetrahedron Letters p. 8067 - 8070 (1997)

Update date:2022-08-03

Topics:

Authors:

Qing, Feng-Ling

Yue, Xiang-Jun

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Article abstract of DOI:10.1016/S0040-4039(97)10246-5

Synthesis of two retinoids in which the 9,13-dicis double bonds were locked in cycloalkene or thiophene was described. The key step was carbonylation of vinyl bromide 9 and 16 with carbon monoxide in the presence ofPd(PPh₃)₄.

Full text of DOI:10.1016/S0040-4039(97)10246-5

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