Nucleosides and Nucleotides p. 1657 - 1660 (1997)
Update date:2022-08-05
Topics:
Wagner, Thomas
Pfleiderer, Wolfgang
We synthesized 3'-O-dimetboxytrityl-5'O-phosphoramidites and 5'-O- succinates which can be used as monomeric building blocks for the built up of oligodeoxyribonucleotides in the alternative 5'-3' direction. With this inverse strategy oligonucleotide 3'-conjugates as well as 3'-3' and 5'-5' internucleotidic linkages can be easily formed.
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