Bioorganic and Medicinal Chemistry Letters p. 1737 - 1740 (1999)
Update date:2022-08-04
Topics:
Aranapakam, Venkatesan
Albright, J. Donald
Grosu, George T.
Delos Santos, Efren G.
Chan, Peter S.
Coupet, Joseph
Ru, Xun
Saunders, Trina
Mazandarani
Synthesis and structure-activity relationships (SAR) of orally active arginine vasopressin (AVP) receptor antagonists are discussed. Potent and orally active AVP receptor antagonists are produced when ring A of VPA-985 (1) is replaced with a 3-pyridinyl unit (2b).
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Doi:10.1016/S0020-1693(97)05792-7
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