Preparation, structural elucidation and reactions of benzyl 2-deoxy-3,5-di-O-methyl-1,4-dithio-L-threo-pentofuranoside and synthesis of the corresponding 2'-deoxy-4'-thionucleosides

Article abstract of DOI:10.1016/S0008-6215(97)00233-4

Benzyl 2-deoxy-3,5-di-O-methyl-1,4-dithio-L-threo-pentofuranoside (5) is synthesized in five steps staring with 2-deoxy-D-ribose. The anomers 5α and 5β are separated and their configuration is unequivocally assigned by use of NOE measurements. 2-Deoxy-3,5