Tetrahedron Letters p. 233 - 236 (1998)
Update date:2022-08-03
Topics:
Rupprecht, Kathleen M.
Baker, Robert K.
Boger, Joshua
Davis, Alita A.
Hodges, Paul J.
Kinneary, Joanne F.
The C10-C17 fragment of the natural product, FK-506, has been stereoselectively synthesized from L-gulose. Methods for elaboration to the C1-C17 fragment and installation of the C9 carbonyl group are described.
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