Synthesis and identification of conformationally constrained selective MMP inhibitors

DOI: 10.1016/S0960-894X(99)00285-1

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1757 - 1760 (1999)

Update date:2022-08-04

Topics:

Authors:

Freskos, John N.

McDonald, Joseph J.

Mischke, Brent V.

Mullins, Patrick B.

Shieh, Huey-Sheng

Stegeman, Roderick A.

Stevens, Anna M.

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Article abstract of DOI:10.1016/S0960-894X(99)00285-1

We have discovered a new series of potent conformationally constrained MMP Inhibitors that are selective for MMP-13 over MMP-1.

Full text of DOI:10.1016/S0960-894X(99)00285-1

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