Bioorganic and Medicinal Chemistry Letters p. 1195 - 1200 (1999)
Update date:2022-08-04
Topics:
Fevig, John M.
Buriak Jr., Joseph
Stouten, Pieter F. W.
Knabb, Robert M.
Gilbert N, Lam
Wong, Pancras C.
Wexler, Ruth R.
The serine protease factor Xa is a critical enzyme in the blood coagulation cascade. Recently, the inhibition of factor Xa has begun to emerge as an attractive strategy for the discovery of novel antithrombotic agents. Here we describe pyrrolidine and isoxazolidine benzamidines as novel and potent inhibitors of factor Xa.
View MoreContact:+86-0512-62857507
Address:Boji Science Park, No1688C,Taishan road, Suzhou ,China
taizhou creating bio-pharm co.,ltd.
Contact:+86- 576- 88827176
Address:715 room ,unit A.junyue Building,Jiaojiang,Taizhou,Zhejiang,China
Onlychem (Jinan)Biotech Co.,Ltd
Contact:86-531-83175885
Address:No. 44, Honglou South Road, Jinan,China
Yixing Bluwat Chemicals Co., Ltd.
Contact:+86 510 87821568
Address:Yongan Road, Yixing Chemical Industrial Park, Yixing, Jiangsu, China
Wuhan Jadechem International Trade Co.,Ltd.
website:http://www.jadechem-intl.com
Contact:+86-27-83527060
Address:Room 502,Building C11,Software new city No.8,Huacheng Avenue,East Lake High-tech development zone,Wuhan,Hubei,China
Doi:10.1021/jo972072n
(1998)Doi:10.1016/S0040-4020(01)93339-3
(1960)Doi:10.1039/b207445a
(2003)Doi:10.1016/S0960-894X(02)00340-2
(2002)Doi:10.1016/S0957-4166(02)00577-3
(2002)Doi:10.1021/jo01339a051
(1966)
