Bioorganic and Medicinal Chemistry Letters p. 1195 - 1200 (1999)
Update date:2022-08-04
Topics:
Fevig, John M.
Buriak Jr., Joseph
Stouten, Pieter F. W.
Knabb, Robert M.
Gilbert N, Lam
Wong, Pancras C.
Wexler, Ruth R.
The serine protease factor Xa is a critical enzyme in the blood coagulation cascade. Recently, the inhibition of factor Xa has begun to emerge as an attractive strategy for the discovery of novel antithrombotic agents. Here we describe pyrrolidine and isoxazolidine benzamidines as novel and potent inhibitors of factor Xa.
View MoreWUXI KINGHAN BIO-MEDICAL&CHEMICAL INC.
Contact:13861062998
Address:Room 1316,No.1619 Huishan Avenue,Wuxi,China
qingdao goldenchem imp and exp co.,ltd.
Contact:532-55579246
Address:no.62 ,haier road laoshan distirct
website:http://www.fwdchem.com
Contact:86-21-54450828
Address:Room 802,Lotus Tower ,159 Tianzhou Road,Xuhui District,Shanghai
website:https://www.sinoshiny.com/products
Contact:+86-20-62802632;62802633
Address:Room 330 GIGCAS Building,No.511 Kehua Street,Tianhe District
Contact:+44 7958 511245
Address:PO Box 469, Manchester, UK
Doi:10.1021/jo972072n
(1998)Doi:10.1016/S0040-4020(01)93339-3
(1960)Doi:10.1039/b207445a
(2003)Doi:10.1016/S0960-894X(02)00340-2
(2002)Doi:10.1016/S0957-4166(02)00577-3
(2002)Doi:10.1021/jo01339a051
(1966)
