The directed lithiation of some 3-acylchromone acetals

DOI: 10.1016/S0040-4039(97)10733-X

Source and publish data:

Tetrahedron Letters p. 1215 - 1218 (1998)

Update date:2022-08-03

Topics:

Authors:

Daia, G. Elena

Gabbutt, Christopher D.

Hepworth, John D.

Heron, B. Mark

Hibbs, David E.

Hursthouse, Michael B.

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Article abstract of DOI:10.1016/S0040-4039(97)10733-X

3-Acylchromone acetals are lithiated at C-2. Subsequent electrophilic trapping gives chromones 4 together with a ring-contracted dimer 6. During the formation of some acetals, an acid-catalysed rearrangement to a 2-substituted 3-formylchromone acetal is observed.

Full text of DOI:10.1016/S0040-4039(97)10733-X

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