
Tetrahedron Letters p. 3865 - 3868 (1994)
Update date:2022-07-29
Topics:
Zhang, Wei
Hua, Ye
Hoge, Garrett
Dowd, Paul
Stereospecific annulation of cyclic alkenes for the preparation of cis-fused seven-membered ring systems was accomplished by sequential [2+2] cycloaddition, exo-allylation, hydrohalogenation, and free radical ring expansion. The new strategy extends our recently developed cyclobutanone-based ring expansion reactions.
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