1-N-Iminosugars: Potent and selective inhibitors of β-glycosidases

DOI: 10.1021/ja973443k

Source and publish data:

Journal of the American Chemical Society p. 3007 - 3018 (1998)

Update date:2022-08-05

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Authors:

Ichikawa, Yoshitaka

Igarashi, Yasuhiro

Ichikawa, Mie

Suhara, Yoshitomo

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Article abstract of DOI:10.1021/ja973443k

A series of 1-N-iminosugars were synthesized to supply the need for glycosidase inhibitors that are both highly potent and selective for β- glycosidases. Designed on the basis of the transition-state model of the β- glucosidase reaction, these iminosugar

Full text of DOI:10.1021/ja973443k

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