Several approaches to cyanide ion-catalyzed synthesis of 4-aroyl-1-phenyl-1h-pyrazolo[3,4-d]pyrimidines

Article abstract of DOI:10.3987/COM-97-S(N)53

- 4-Aroyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidines (5) were formed in low yields by reaction of 4-chloro-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine (4) with arenecarbaldehydes (3) in the presence of potassium cyanide. Similar reaction of 4-tosyl-1-phenyl-1H-pyra