Strigol and sorgolactone synthetic studies use of Winferfeldt's template to control the C-2' configuration

Article abstract of DOI:10.1016/S0040-4039(97)01228-8

A route comprising (i) a cycloaddition reaction of citraconic anhydride with the Winterfeldt auxiliary, (ii) hydride reduction of the cycloadduct, (iii) a (formal) ether formation, and (iv) a cycloreversion reaction allows efficient stereocontrol at C-2' in the synthesis of strigol and its structural analogues.