Structural determinants of AMPA agonist activity in analogues of 2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid: Synthesis and pharmacology

DOI: 10.1021/jm0003586

Source and publish data:

Journal of Medicinal Chemistry p. 4910 - 4918 (2000)

Update date:2022-08-04

Topics:

Authors:

Bang-Andersen

Ahmadian

Lenz Lenz

Stensb?l

Madsen Madsen

Bogeso Bogeso

Krogsgaard-Larsen

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Article abstract of DOI:10.1021/jm0003586

We have previously shown that the 2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor agonist, 2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid (ACPA, 2), binds to AMPA receptors in a manner different from that of AMPA (1) i

Full text of DOI:10.1021/jm0003586

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