Bioorganic and Medicinal Chemistry Letters p. 533 - 538 (1999)
Update date:2022-08-03
Topics:
Nomura, Masahiro
Kinoshita, Susumu
Satoh, Hiroya
Maeda, Toshio
Murakami, Koji
Tsunoda, Masaki
Miyachi, Hiroyuki
Awano, Katsuya
A series of 3-[(2,4-dioxothiazolidin-5-yl)methyl]benzamide derivatives was prepared as part of a search for antidiabetic agents. A structure- activity relationship study of these compounds led to the identification of 5-[(2,4-dioxothiazolidin-5-yl)methyl]-2-methoxy-N-[[4- (trifluoromethyl)phenyl]methyl]benzamide (KRP-297) as a candidate drug for the treatment of diabetes mellitus.
View MoreTIANJIN ZHONGXIN CHEMTECH CO.,LTD.
Contact:86-022-66880623
Address:FINANCIAL STREET WEST BLK 7, #308, NO.52 XINCHENG WEST ROAD, TEDA, TIANJIN, P.R.CHINA
HANGZHOU FOREWIN PHARMA CO., LTD
Contact:+86-571-89053961
Address:hangzhou
SHANGHAI RC CHEMICALS CO.,LTD.
website:http://www.rcc.net.cn
Contact:+86-21-50322175
Address:Rm1415 Yinqiao Masion No.58 Jinxin Road Pudong Shanghai China
Tianjin Chemsyntech Chemical Co., Ltd
Contact:+86-22-60872258
Address:Haitai green industry base in Tianjin, K1,5-601
Shaanxi Lighte Optoelectronics Material Co., Ltd.
Contact:+86-29-88320728-622/619/620
Address:No.55 INDUSTRY ROAD 2,XI'AN NATIONAL CIVIL AEROSPACE INDUSTRIAL PARK.XI'AN China 710065.
Doi:10.1002/anie.201701691
(2017)Doi:10.1016/S0040-4020(98)00102-1
(1998)Doi:10.1016/S0957-4166(98)00040-8
(1998)Doi:10.1021/ja01018a027
(1968)Doi:10.1016/j.jorganchem.2015.07.017
(2015)Doi:10.1002/cmdc.201700243
(2017)
