Bioorganic and Medicinal Chemistry Letters p. 533 - 538 (1999)
Update date:2022-08-03
Topics:
Nomura, Masahiro
Kinoshita, Susumu
Satoh, Hiroya
Maeda, Toshio
Murakami, Koji
Tsunoda, Masaki
Miyachi, Hiroyuki
Awano, Katsuya
A series of 3-[(2,4-dioxothiazolidin-5-yl)methyl]benzamide derivatives was prepared as part of a search for antidiabetic agents. A structure- activity relationship study of these compounds led to the identification of 5-[(2,4-dioxothiazolidin-5-yl)methyl]-2-methoxy-N-[[4- (trifluoromethyl)phenyl]methyl]benzamide (KRP-297) as a candidate drug for the treatment of diabetes mellitus.
View MoreQINGDAO TAOSIGN INTERNATIONAL TRADE CO.,LIMITED
Contact:+86-0532-82683616
Address:RM1402, Doublestar Seacoase 7#, No. 5 Guizhou Road, Qingdao, Shandong, China
Pengchen New Material Technology Co., Ltd.
Contact:+86-512-63680537
Address:99.6 km of national road 318, Meiyan Community,Pingwang Town, Wujiang District, Suzhou 215225
Beijing Green Guardee Technology CO,.LTD
Contact:+86-10-69706062
Address:F2 BLdj,5 No.37 Chaoqian Road
SINO Industries Company Limited(expird)
Contact:86-29-85369724
Address:No.111, Jiefang Road, Xi’an, China
lianyungang jinkang pharmaceutical technology co., ltd.
Contact:008651885445517
Address:Jinshan industrial park, Ganyu county, Lianyungang, Jiangsu Province, 222115, China
Doi:10.1002/anie.201701691
(2017)Doi:10.1016/S0040-4020(98)00102-1
(1998)Doi:10.1016/S0957-4166(98)00040-8
(1998)Doi:10.1021/ja01018a027
(1968)Doi:10.1016/j.jorganchem.2015.07.017
(2015)Doi:10.1002/cmdc.201700243
(2017)
