Novel nonsteroidal selective estrogen receptor modulators. Carbon and heteroatom replacement of oxygen in the ethoxypiperidine region of raloxifene

DOI: 10.1016/S0960-894X(99)00050-5

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 523 - 528 (1999)

Update date:2022-08-05

Topics: Heteroatom Nonsteroidal

Authors:

Schmid, Christopher R.

Sluka, James P.

Duke, Kristen M.

Glasebrook, Andrew W.

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Article abstract of DOI:10.1016/S0960-894X(99)00050-5

Compounds were synthesized where oxygen in the ethoxypiperidine region of raloxifene is replaced with carbon, sulfur, or nitrogen linkages. Thia- and aza-substituted compounds were prepared by novel methodology. The compounds were evaluated in vitro as se

Full text of DOI:10.1016/S0960-894X(99)00050-5

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Product name:4-[methyl-(2-piperidin-1-yl-ethyl)-amino]-benzoic acid methyl ester

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