Bioorganic Chemistry p. 307 - 319 (1997)
Update date:2022-08-05
Topics:
Itoh, Kunihiko
Sekizaki, Haruo
Toyota, Eiko
Tanizawa, Kazutaka
Methyltrypsin-catalyzed peptide synthesis has been studied by using conventional alkyl ester and p-guanidinophenyl ester derivatives of α-amino acid as the acyl donor component. They were found to be coupled with α- amino acid derivatives (acyl acceptor component) to produce dipeptide. The behavior of methyltrypsin toward both the substrates has been studied.
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