Tetrahedron Letters p. 2425 - 2428 (1998)
Update date:2022-08-05
Topics:
Barrero, Alejandro F.
Alvarez-Manzaneda, Enrique J.
Herrador, M. Mar
Valdivia, Monica V.
Chahboun, Rachid
Compounds 7-8, monoterpenic analogues of the marine metabolites puupehenone (1) and puupehedione (2), were prepared from the easily available β-cylocitral (10) an the aryllithium derived from 11 and 12. 8 showed antitumoral activity 4-10 times higher than that for the natural products.
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